Clinical / Biochemical

• Assessment of nutritional status, Water and electrolyte metabolism, acid base homoeostasis, renal physiology, endocrinology and chemical pathology.

Analytical / Managerial

• Ion specific electrodes, osmometry, methods of quality control

1. Demonstrate an advanced knowledge of the structure and function of the nephron and the laboratory assessment of kidney function
2. Demonstrate a basic understanding of water and electrolyte metabolism and its dysfunction in simple clinical situations
3. Demonstrate a basic understanding of acid/base metabolism and its disorders
4. Demonstrate an advanced understanding of renal failure and its metabolic consequences
5. Understand the basics of nutritional support and the laboratory’s role in total parenteral nutrition
6. Demonstrate an advanced understanding of the principles and practice of an agreed range of analytical methods.

                          

Clinical / Biochemical

• Carbohydrates and diabetes, mechanisms of insulin action, classification of diabetes, investigation and treatment of diabetes, assessment of diabetic control, complications of diabetes, hyperosmolar coma, ketoacidosis, hypoglycaemia
• Lipid metabolism hyperlipidaemia investigation and treatment

Analytical

Methods of protein separation, principles of dry chemistry, laboratory assessment of abnormal lipid metabolism, ultracentrifugation, apolipoprotein estimation

1. Demonstrate an advanced knowledge of glucose metabolism and how it is disordered in Diabetes
2. Evaluate the laboratory’s role in screening, diagnosis, monitoring and management of diabetes mellitus and insulin-resistant syndromes
3. Demonstrate an advanced understanding of the causes of Diabetic complications
4. Demonstrate an advanced knowledge of the structure and function of lipids and their role as risk factors
5. Evaluate the laboratory’s role in the investigation of hyperlipidaemia and CHD risk assessment
6. Discuss myeloma, haematological malignancies and the investigation of paraproteinaemia
7. Demonstrate an advanced understanding of the principles and practice of an agreed range of analytical methods.