Essay Paper 16th July 2004
Time allowed 3 hours
Answer 4 questions. Starting each question on a new sheet of paper labelled with the question number and your name.
- Write an account of the pre-analytical factors that may influence hormone measurements in blood, and how they may affect their interpretation. Illustrate your answer with examples.
- Critically discuss the laboratory assessment of glomerular function in man.
- Give an account of the methods currently used for the measurement of haemoglobin A1C and discuss the issues surrounding their standardisation.
- Write an essay on the patho-physiological consequences of insulin deficiency.
- Discuss the differential diagnosis and biochemical investigations that should be considered in the case of a 39 year old lady found to have hypercalcaemia.
- Write an essay on the regulation of extra-cellular fluid potassium concentration illustrating your account with examples of pathological states that may critically affect it.
